ball miller for cocrystal insrtument

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Synthesis and characterization of a (+)echin and L

On this basis and in order to use a green method which avoids the employment of large amount of solvent, the cocrystal ASC was also prepared through Liquid Assisted Grinding (LAG). Here, LAG was performed by adding a small amount of ethanol during the grinding of the starting materials in an agate ball miller for 3 h.

Pharmaceutical Cocrystals: New Solid Phase Modifiion

Jan 25, 2018 · The solid materials that will result in the cocrystal are admixed in appropriate stoichiometric amounts, pressed and crushed together with a mortar and pestle, or a ball mill or vibrator mill. The common grinding duration ranges from 30 to 60 min.

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(PDF) Synthesis and characterization of a (+)echin and

In this context, the synthesis of a cocrystal between (+)echin and L(+)ascorbic acid, was proved to be a useful strategy to make a new ingredient able to ameliorate the antioxidant profile

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Synthesis and characterization of a (+)echin and L

The cocrystal ASC was prepared also by Liquid Assisted Grinding (LAG). (+)echin (50 mg, 0.172 mmol) and L(+)ascorbic acid (30.3 mg, 0.172 mmol) were grinded in an agate ball miller for 3 h in the presence of a small amount of ethanol (20 μL). The resulting powder was analysed by PXRD.